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December 15, 2025

January 2026 HCPCS Updates – New, Revised, and Discontinued HCPCS Codes and Modifiers

The following information is based on the January 2026 Healthcare Common Procedure Coding System (HCPCS) file. There are several updates that will be effective January 1, 2026. Please keep in mind that the appearance of a HCPCS code is not an indication of coverage by the DME MAC.

This following list contains added HCPCS codes that will be effective January 1, 2026.

HCPCS DESCRIPTION
A4295 Intermittent urinary catheter; straight tip, hydrophilic coating, each
A4296 Intermittent urinary catheter; coude (curved) tip, hydrophilic coating, each
A4297 Intermittent urinary catheter; hydrophilic coating, with insertion supplies
J0013 Esketamine, nasal spray, 1 mg
J0162 Injection, epinephrine (fresenius), not therapeutically equivalent to j0165, 0.1 mg
J0654 Injection, liothyronine, 1 mcg
J1073 Testosterone pellet, implant, 75 mg
J1736 Injection, meloxicam (delova), 1 mg
J1737 Injection, meloxicam (azurity), 1 mg
J1837 Injection, posaconazole, 1 mg
J2516 Injection, pentamidine isethionate, 1 mg
J2596 Injection, vasopressin (long grove), not therapeutically equivalent to j2598, 1 unit
J2711 Injection, neostigmine methylsulfate 0.1 mg and glycopyrrolate 0.02 mg
J3291 Injection, tranexamic acid in sodium chloride, 5 mg
J3376 Injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg
J3379 Injection, valproate sodium, 5 mg
J3387 Injection, elivaldogene autotemcel, per treatment
J3389 Topical administration, prademagene zamikeracel, per treatment
J7299 Intrauterine copper contraceptive (miudella)
J7528 Mycophenolate mofetil, for suspension, oral, 100 mg
J9184 Injection, gemcitabine hydrochloride (avyxa), 200 mg
J9256 Injection, nipocalimab-aahu, 3 mg
J9282 Mitomycin, intravesical instillation, 1 mg
J9326 Injection, telisotuzumab vedotin-tllv, 1 mg

The following HCPCS codes have description/verbiage changes that will be effective January 1, 2026.

HCPCS DESCRIPTION
A4351 Intermittent urinary catheter; straight tip, with or without coating (teflon, silicone, or silicone elastomer, etc.), each
A4352 Intermittent urinary catheter; coude (curved) tip, with or without coating (teflon, silicone, or silicone elastomeric, etc.), each

The following list contains discontinued HCPCS codes, along with the cross-walked HCPCS codes (if applicable). Please note, not all discontinued HCPCS codes will have a cross-walked HCPCS code.

HCPCS DISCONTINUE DATE CROSSWALK HCPCS CODE
J0172 12/31/2025  
J0190 12/31/2025  
J0200 12/31/2025  
J0205 12/31/2025  
J0215 12/31/2025  
J0288 12/31/2025  
J0350 12/31/2025  
J0365 12/31/2025  
J0380 12/31/2025  
J0395 12/31/2025  
J0710 12/31/2025  
J0715 12/31/2025  
J0795 12/31/2025  
J0889 12/31/2025  
J1267 12/31/2025  
J1330 12/31/2025  
J1443 12/31/2025  
J1444 12/31/2025  
J1445 12/31/2025  
J1452 12/31/2025  
J1457 12/31/2025  
J1562 12/31/2025  
J1572 12/31/2025  
J1620 12/31/2025  
J1655 12/31/2025  
J1710 12/31/2025  
J1945 12/31/2025  
J2504 12/31/2025  
J2513 12/31/2025  
J2910 12/31/2025  
J2940 12/31/2025  
J2995 12/31/2025  
J3280 12/31/2025  
J3305 12/31/2025  
J3310 12/31/2025  
J3320 12/31/2025  
J3355 12/31/2025  
J3364 12/31/2025  
J3365 12/31/2025  
J3400 12/31/2025  
J7505 12/31/2025  
J8562 12/31/2025  
J8650 12/31/2025  
J9019 12/31/2025  
J9020 12/31/2025  
J9098 12/31/2025  
J9151 12/31/2025  
J9165 12/31/2025  
J9212 12/31/2025  
J9270 12/31/2025  
Q0174 12/31/2025  
Q5109 12/31/2025  

You can find excel versions of this document on the CMS website: HCPCS Quarterly UpdateExternal Website.

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